Local runners and walkers can work up an appetite Thanksgiving morning, as the Knoxville Cancer Relay team hosts its inaugural Turkey Trot event at the Knoxville Recreation Center, 800 S. Park Lane. The 5K event starts at 8 a.m. and is a head start for the Relay Team’s 2025 efforts on behalf of the American Cancer Society. Registration is $35 and you can sign up online here or at the rec center on the morning of the Turkey Trot.